Search Result

Results for "

and R5/W677

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fat Mass and Obesity-associated Protein (FTO) (2) 11β-HSD (1) 5-HT Receptor (10) ADC Linker (1) Adrenergic Receptor (2) Akt (4) Amino Acid Derivatives (1128) Amylin Receptor (2) Amyloid-β (1) Anaplastic lymphoma kinase (ALK) (1) Angiotensin-converting Enzyme (ACE) (2) Antibiotic (8) Apoptosis (40) ATM/ATR (1) Autophagy (6) Bacterial (22) Beta-lactamase (1) Biochemical Assay Reagents (81) c-Kit (1) c-Met/HGFR (3) c-Myc (1) Calcium Channel (3) Cannabinoid Receptor (1) Carbonic Anhydrase (2) Casein Kinase (1) Caspase (2) Cathepsin (4) CCR (1) CD28 (2) CDK (5) CGRP Receptor (1) Checkpoint Kinase (Chk) (2) Cholinesterase (ChE) (2) Complement System (1) COX (4) CXCR (3) Cytochrome P450 (2) Dihydrofolate reductase (DHFR) (3) Dipeptidyl Peptidase (1) DNA/RNA Synthesis (44) Dopamine Receptor (1) Dopamine β-hydroxylase (1) Drug Metabolite (3) E1/E2/E3 Enzyme (3) EBV (1) EGFR (5) Endogenous Metabolite (39) Ephrin Receptor (1) Epigenetic Reader Domain (7) ERK (2) Ferroptosis (2) FGFR (1) FLT3 (1) Fluorescent Dye (10) Formyl Peptide Receptor (FPR) (2) Fungal (6) GABA Receptor (1) Galectin (1) Glucosidase (3) Glutathione Peroxidase (1) GSK-3 (3) Guanylate Cyclase (1) HDAC (4) HIF/HIF Prolyl-Hydroxylase (1) Histamine Receptor (3) Histone Acetyltransferase (1) Histone Demethylase (3) Histone Methyltransferase (1) HIV (5) HMG-CoA Reductase (HMGCR) (2) HSP (1) HSV (1) ICMT (1) IFNAR (1) IGF-1R (1) iGluR (1) Indoleamine 2,3-Dioxygenase (IDO) (2) Influenza Virus (2) Insulin Receptor (2) Integrin (3) Interleukin Related (7) Isotope-Labeled Compounds (13) JAK (2) Keap1-Nrf2 (1) Ligands for E3 Ligase (4) Ligands for Target Protein for PROTAC (1) Liposome (4) Lipoxygenase (1) mAChR (1) MDM-2/p53 (4) MEK (1) Melanocortin Receptor (1) Microtubule/Tubulin (1) Mineralocorticoid Receptor (1) MMP (7) Monoamine Oxidase (9) mTOR (2) nAChR (1) Neuropeptide Y Receptor (3) NF-κB (5) NO Synthase (2) Notch (3) Nucleoside Antimetabolite/Analog (19) Opioid Receptor (3) Orexin Receptor (OX Receptor) (1) Orthopoxvirus (1) Oxidative Phosphorylation (1) Oxytocin Receptor (2) P-glycoprotein (1) p38 MAPK (2) Parasite (7) PARP (1) PD-1/PD-L1 (2) PDGFR (1) PGE synthase (1) Phosphatase (3) Phospholipase (1) PI3K (1) Pim (2) PKC (1) PKG (1) Potassium Channel (5) Prostaglandin Receptor (2) PROTACs (1) Proteasome (1) Pyruvate Kinase (1) Raf (2) RANKL/RANK (1) Ras (2) Reactive Oxygen Species (5) Reverse Transcriptase (1) ROS Kinase (1) SARS-CoV (1) Ser/Thr Protease (3) Small Interfering RNA (siRNA) (7) Sodium Channel (6) STAT (1) Stearoyl-CoA Desaturase (SCD) (1) STING (1) Survivin (1) TAM Receptor (1) Telomerase (1) TGF-β Receptor (1) Tie (1) TNF Receptor (2) Topoisomerase (4) Trk Receptor (1) TRP Channel (6) Tryptophan Hydroxylase (1) Vasopressin Receptor (4) VEGFR (4) Wnt (2) β-catenin (2)
By Research Areas:	Cancer (154) Cardiovascular Disease (24) Endocrinology (7) Infection (52) Inflammation/Immunology (68) Metabolic Disease (45) Neurological Disease (67)
Click Chemistry:	Azide (5) Alkynes (6)

1619

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

1271

Peptides

Inhibitory Antibodies

Natural
Products

275

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: Fat Mass and Obesity-associated Protein (FTO)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-103156

NAS-181 dimesylate 1 Publications Verification	5-HT Receptor	Neurological Disease
NAS181 is a potent and selective antagonist of rat 5-HT_1B receptor, with a K_i of 47 nM. NAS181 shows 13-fold selectivity for r5-HT_1B over bovine 5-HT_1B receptor (K_i=630 nM). NAS181 increases the 5-HT turnover and the synaptic concentration of 5-HT by inhibiting terminal r5-HT_1B autoreceptors .

HY-13406

TAK-779 2 Publications Verification Takeda 779	CCR HIV CXCR	Infection Inflammation/Immunology Endocrinology
TAK-779 is a potent and selective nonpeptide antagonist of *CCR5* and CXCR3, with a K_i of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC₅₀ and EC₉₀ of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells.

HY-15971

AMD 3465 hexahydrobromide 4 Publications Verification GENZ-644494 hexahydrobromide	CXCR HIV	Infection Endocrinology
AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12 ^AF647 to CXCR4, with IC₅₀s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC₅₀: 1-10 nM), but has no effect on CCR5-using (R5) viruses.

HY-135507

NAS-181	5-HT Receptor	Neurological Disease
NAS-181 is a potent and selective rat 5-hydroxytryptamine1B (r5-HT1B) antagonist with an K_i value of 47 nM. NAS-181 increases the 5-HTP accumulation in rat brain regions .

HY-15971A

AMD 3465 GENZ-644494	CXCR HIV	Infection Endocrinology
AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12 ^AF647 to CXCR4, with IC₅₀s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC₅₀: 1-10 nM), but has no effect on CCR5-using (R5) viruses.

HY-103693

NAZ2329 1 Publications Verification	Phosphatase	Cancer
NAZ2329, the first cell-permeable inhibitor of R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), allosterically and preferentially inhibits PTPRZ (IC₅₀=7.5 µM for hPTPRZ1) and PTPRG (IC₅₀=4.8 µM for hPTPRG) over other PTPs. NAZ2329 binds to the active D1 domain and more potently inhibits PTPRZ-D1 fragment (IC₅₀ of 1.1 µM) than the whole intracellular (D1 + D2) fragment (IC₅₀ of 7.5 µM). NAZ2329 can effectively inhibit tumor growth of the glioblastoma cells and suppress stem cell-like properties .

HY-134851

HIV-1 inhibitor-6	HIV	Infection
HIV-1 inhibitor-6 (compound 9), a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor. HIV-1 inhibitor-6 blocks HIV replication. HIV-1 inhibitor-6 is active against wild-type HIV-1IIIB (subtype B, X4-tropic) and HIV-1 97USSN54 (subtype A, R5-tropic) with EC₅₀s of 0.6 μM and 0.9 μM, respectively. HIV-1 inhibitor-6 inhibits HIV strains resistant to agents targeting HIV reverse transcriptase, protease, integrase, and coreceptor CCR5 with EC₅₀s ranging from 0.9 to 1.5 μM .

HY-100754B

(2R,5S)-Ritlecitinib (2R,5S)-PF-06651600	JAK	Inflammation/Immunology
(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective JAK3 inhibitor (IC₅₀=144.8 nM) extracted from patent US20150158864A1, example 68 .

HY-14664F

(3R,5S)-Fluvastatin sodium (3R,5S)-XU 62-320	HMG-CoA Reductase (HMGCR) Autophagy	Cancer
(3R,5S)-Fluvastatin ((3R,5S)-XU 62-320) sodium is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .

HY-W002304

(R)-5-Oxopyrrolidine-2-carboxylic acid

Endogenous Metabolite Metabolic Disease

(R)-5-Oxopyrrolidine-2-carboxylic acid is an endogenous metabolite.
HY-Z5058S

(3R,5S)-Fluvastatin-d7 sodium

(3R,5S)-XU 62-320-d₇
Isotope-Labeled Compounds Others

(3R,5S)-Fluvastatin-d₇ (sodium) is the deuterium labeled (3R,5S)-Fluvastatin sodium[1].

*(R)-5-Oxopyrrolidine-2-carboxylic acid*	Endogenous Metabolite	Metabolic Disease
(R)-5-Oxopyrrolidine-2-carboxylic acid is an endogenous metabolite.

(3R,5S)-Fluvastatin-d7 sodium (3R,5S)-XU 62-320-d₇	Isotope-Labeled Compounds	Others
(3R,5S)-Fluvastatin-d₇ (sodium) is the deuterium labeled (3R,5S)-Fluvastatin sodium[1].

HY-109022A

(3R,5R,6S)-Atogepant (3R,5R,6S)-MK-8031; (3R,5R,6S)-AGN-241689	CGRP Receptor	Neurological Disease
(3R,5R,6S)-Atogepant ((3R,5R,6S)-MK-8031) is the enantiomer of Atogepant (HY-109022). Atogepant is a calcitonin gene-related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine.

HY-14664B

(3R,5S)-Fluvastatin (3R,5S)-XU 62-320 free acid
(3R,5S)-Fluvastatin is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC₅₀ of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .

HY-135406

(3R,5R)-Rosuvastatin Lactone

Others Cardiovascular Disease Metabolic Disease

(3R,5R)-Rosuvastatin Lactone is an isomer of Rosuvastatin Lactone.

(3R,5R)-Rosuvastatin Lactone	Others	Cardiovascular Disease Metabolic Disease
(3R,5R)-Rosuvastatin Lactone is an isomer of Rosuvastatin Lactone.

HY-17504C

(3R,5R)-Rosuvastatin	HMG-CoA Reductase (HMGCR) Potassium Channel Autophagy	Cardiovascular Disease Metabolic Disease
(3R,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC₅₀ of 11 nM . Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC₅₀ of 195 nM . Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .

HY-N5054

*(R)-5,7-Dimethoxyflavanone*	TNF Receptor	Inflammation/Immunology
(R)-5,7-Dimethoxyflavanone shows potent antimutagenic activity against MeIQ mutagenesis in Ames test using the S. typhimurium TA100 and TA98 strains . And (R)-5,7-Dimethoxyflavanone significantly and dose-dependently inhibits the inflammatory mediato .

HY-N10405

*(R)-5-Hydroxy-1,7-diphenyl-3-heptanone*	Keap1-Nrf2	Metabolic Disease
(R)-5-Hydroxy-1,7-diphenyl-3-heptanone is a diarylheptanoid that can be found in Alpinia officinarum. (R)-5-Hydroxy-1,7-diphenyl-3-heptanone ameliorates oxidative stress and insulin resistance via activation of Nrf2/ARE pathway .

HY-162083

CB2R/5-HT1AR agonist 1	Cannabinoid Receptor 5-HT Receptor	Neurological Disease
CB2R/5-HT1AR agonist 1 (Compound 2o) is an orally active partial agonist of the CB₂ receptor (EC₅₀=479.6 nM). CB2R/5-HT1AR agonist 1 is a full agonist of *5-HT_1A* receptor (EC₅₀=2.7 μM). CB2R/5-HT1AR agonist 1 exhibits anti-anxiety and anti-depressive effects. CB2R/5-HT1AR agonist 1 possesses favorable pharmacokinetic properties .

HY-113025A

L-hydroxylysine dihydrochloride (2S,5R)-5-Hydroxylysine dihydrochloride	Endogenous Metabolite	Others
L-hydroxylysine dihydrochloride ((2S,5R)-5-Hydroxylysine dihydrochloride), an amino acid, is exclusive to collagen protein, which is formed by posttranslational hydroxylation of some lysine residues .

HY-135374

(3R,5S)-Atorvastatin sodium	Drug Metabolite	Metabolic Disease Inflammation/Immunology
(3R,5S)-Atorvastatin sodium is an impurity of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion with IC₅₀s of 0.39 μM and 2.39 μM, respectively .

HY-P9974

Vantictumab OMP-18R5	Wnt	Cancer
Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to *FZD1/2/5/7/8* receptors. Vantictumab is being studied against cancers such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma .

HY-19322C

(1S,3R,5R)-PIM447 dihydrochloride (1S,3R,5R)-LGH447 dihydrochloride	Pim	Cancer
(1S,3R,5R)-PIM447 (dihydrochloride) an PIM inhibitor extracted from patent US 20100056576 A1, compound example 72, has IC₅₀ values of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3.

HY-RS10540

PIK3R5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PIK3R5 Human Pre-designed siRNA Set A contains three designed siRNAs for PIK3R5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIK3R5 Human Pre-designed siRNA Set A PIK3R5 Human Pre-designed siRNA Set A

HY-RS14219

TAS2R5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TAS2R5 Human Pre-designed siRNA Set A contains three designed siRNAs for TAS2R5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TAS2R5 Human Pre-designed siRNA Set A TAS2R5 Human Pre-designed siRNA Set A

HY-P99320

Tarextumab OMP 59R5; Anti-Human NOTCH2 Recombinant Antibody	Notch	Cancer
Tarextumab (OMP-59R5) is an anti-Notch2/3 fully human IgG2 monoclonal antibody. Tarextumab shows anti-tumor activity .

HY-160251

3-HC-Gluc (3'R,5k'S)-trans-3'-Hydroxycotinine glucuronide	Others	Others
3-HC-Gluc ((3’R,5k’s)-trans-3’ -Hydroxycotinine glucuronide) The trans-structure of 3-HC, the main metabolite of nicotine .

HY-RS11018

PPP2R5A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPP2R5A Human Pre-designed siRNA Set A contains three designed siRNAs for PPP2R5A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPP2R5A Human Pre-designed siRNA Set A PPP2R5A Human Pre-designed siRNA Set A

HY-RS11019

PPP2R5B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPP2R5B Human Pre-designed siRNA Set A contains three designed siRNAs for PPP2R5B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPP2R5B Human Pre-designed siRNA Set A PPP2R5B Human Pre-designed siRNA Set A

HY-RS11020

PPP2R5C Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPP2R5C Human Pre-designed siRNA Set A contains three designed siRNAs for PPP2R5C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPP2R5C Human Pre-designed siRNA Set A PPP2R5C Human Pre-designed siRNA Set A

HY-RS11021

PPP2R5D Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPP2R5D Human Pre-designed siRNA Set A contains three designed siRNAs for PPP2R5D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPP2R5D Human Pre-designed siRNA Set A PPP2R5D Human Pre-designed siRNA Set A

HY-RS11022

PPP2R5E Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PPP2R5E Human Pre-designed siRNA Set A contains three designed siRNAs for PPP2R5E gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPP2R5E Human Pre-designed siRNA Set A PPP2R5E Human Pre-designed siRNA Set A

HY-W040240S

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one-13C	Isotope-Labeled Compounds Endogenous Metabolite	Others
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- ¹³C is the ¹³C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].

HY-163230

(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc	Ligands for E3 Ligase Autophagy	Cancer
(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-128836

(4R,5S)-Nutlin carboxylic acid MDM2 ligand 2; E3 ligase Ligand 15	Ligands for E3 Ligase	Cancer
(4R,5S)-Nutlin carboxylic acid (MDM2 ligand 2) is the Nutlin 3-based MDM2 ligand. (4R,5S)-Nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTACs .

HY-78899A

(4R,5S)-Monomethyl auristatin E intermediate-6	Others	Cancer
(4R,5S)-Monomethyl auristatin E intermediate-6 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs) .

HY-146708S

((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate-15N4 sodium	Isotope-Labeled Compounds	Others
((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- ¹⁵N₄ (sodium) is a ¹⁵N-labeled ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate (so

HY-W040240

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one

Endogenous Metabolite Metabolic Disease

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite.

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one	Endogenous Metabolite	Metabolic Disease
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite.

HY-W040240S1

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one-13C-1	Isotope-Labeled Compounds Endogenous Metabolite	Others
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- ¹³C-1 is the ¹³C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].

HY-W040240S2

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one-13C-2	Isotope-Labeled Compounds Endogenous Metabolite	Others
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- ¹³C-2 is the ¹³C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].

HY-43426

*(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose*	Nucleoside Antimetabolite/Analog	Cancer
(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W011090S

((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate-13C9,15N3 sodium CMP-¹³C₉,¹⁵N₃	Isotope-Labeled Compounds	Others
((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- ¹³C₉, ¹⁵N₃ (sodium) is the ¹³C and ¹⁵N labeled Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate[1].

HY-78746A

(3S,4R,5S)-rel-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxylic acid	Amino Acid Derivatives	Others
D-Proline, 3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-, (3S,4R,5S)-rel- is a proline derivative .

HY-N9093

(3R,5R)-3,5-Diacetoxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane	Others	Inflammation/Immunology Cancer
(3R,5R)-3,5-Diacetoxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane, a diarylheptanoid from the rhizomes of Curcuma kwangsiensis, possesses a variety of biological and pharmacological activities including antioxidant, antihepa totoxic, anti-inflammatory, antiproliferative, antiemetic, and antitumor activities .

HY-W091788

(2S,3R,5S)-7-Deaza-2'-deoxy-7-iodoadenosine	Others	Others
(2S,3R,5S)-7-Deaza-2'-deoxy-7-iodoadenosine is the isomer of 7-Deaza-2'-deoxy-7-iodoadenosine (HY-W048490), and can be used as an experimental control. 7-Deaza-2'-deoxy-7-iodoadenosine is a modified oligonucleotide containing 7-Deazaadenine .

HY-163226

(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc	Ligands for E3 Ligase Autophagy	Cancer
(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

HY-P4210

Sulanemadlin ALRN-6924; MP-4897	MDM-2/p53	Cancer
Sulanemadlin (ALRN-6924) is a potent and cell-permeating p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2, p53-MDMX, or both p53 and MDM2 and MDMX protein-protein interactions. Sulanemadlin can be used for cancers research .

HY-P5984

Thioether-cyclized helix B peptide, CHBP	mTOR	Others
Thioether-cyclized helix B peptide, CHBP can improve metabolic stability and renoprotective effect through inducing autophagy via inhibition of mTORC1 and activation of mTORC2 .

HY-P5984A

Thioether-cyclized helix B peptide, CHBP TFA	mTOR	Others
Thioether-cyclized helix B peptide, CHBP (TFA) is the TFA form of Thioether-cyclized helix B peptide, CHBP (HY-P5984). Thioether-cyclized helix B peptide, CHBP (TFA) can improve metabolic stability and renoprotective effect through inducing autophagy via inhibition of mTORC1 and activation of mTORC2 .

HY-P5145

μ-Conotoxin PIIIA

Sodium Channel Inflammation/Immunology

μ-Conotoxin PIIIA is a sodium channel (NaV 1.4) blocker. μ-Conotoxin PIIIA can be isolated from Conus purpurascens .

HY-P5864

µ-Conotoxin BuIIIA	Sodium Channel	Neurological Disease
μ-Conotoxin BuIIIA (Mu-Conotoxin BuIIIA) is a voltage-gated sodium channel (VGSC) blocker. μ-Conotoxin BuIIIA is a toxic peptide that can be obtained from the venom of Cone snails. μ-Conotoxin BuIIIA can be used in the study of neurological diseases .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W002304

*(R)-5-Oxopyrrolidine-2-carboxylic acid*	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(R)-5-Oxopyrrolidine-2-carboxylic acid is an endogenous metabolite.

HY-N5054

*(R)-5,7-Dimethoxyflavanone*	Structural Classification Flavonoids other families Classification of Application Fields Flavonones Source classification Plants Inflammation/Immunology Disease Research Fields	TNF Receptor
(R)-5,7-Dimethoxyflavanone shows potent antimutagenic activity against MeIQ mutagenesis in Ames test using the S. typhimurium TA100 and TA98 strains . And (R)-5,7-Dimethoxyflavanone significantly and dose-dependently inhibits the inflammatory mediato .

HY-N10405

*(R)-5-Hydroxy-1,7-diphenyl-3-heptanone*	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Alpinia officinarum Hance Plants Disease Research Fields Zingiberaceae	Keap1-Nrf2
(R)-5-Hydroxy-1,7-diphenyl-3-heptanone is a diarylheptanoid that can be found in Alpinia officinarum. (R)-5-Hydroxy-1,7-diphenyl-3-heptanone ameliorates oxidative stress and insulin resistance via activation of Nrf2/ARE pathway .

HY-W040240

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite.

HY-113025A

L-hydroxylysine dihydrochloride (2S,5R)-5-Hydroxylysine dihydrochloride	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-hydroxylysine dihydrochloride ((2S,5R)-5-Hydroxylysine dihydrochloride), an amino acid, is exclusive to collagen protein, which is formed by posttranslational hydroxylation of some lysine residues .

HY-N9093

(3R,5R)-3,5-Diacetoxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane	Source classification Phenols Curcuma kwangsiensis S. K. Lee & C. F. Liang Plants Zingiberaceae	Others
(3R,5R)-3,5-Diacetoxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane, a diarylheptanoid from the rhizomes of Curcuma kwangsiensis, possesses a variety of biological and pharmacological activities including antioxidant, antihepa totoxic, anti-inflammatory, antiproliferative, antiemetic, and antitumor activities .

HY-N1459

Campesterol 1 Publications Verification (24R)-5-Ergosten-3β-ol	Structural Classification Microorganisms other families Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields Steroids Cancer	Endogenous Metabolite
Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

HY-121401A

(−)-Myrtenal (1R)-(−)-Myrtenal; (−)-(1R,5S)-Myrtenal	Other Monoterpenes Classification of Application Fields Terpenoids Labiatae Source classification Metabolic Disease Erythrina poeppigiana Plants Disease Research Fields	Akt
(−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats .

HY-N1459R

Campesterol (Standard) (24R)-5-Ergosten-3β-ol (Standard)	Structural Classification other families Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields Steroids Cancer	Endogenous Metabolite
Campesterol (Standard) is the analytical standard of Campesterol. This product is intended for research and analytical applications. Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

HY-139637

(±)-Silybin Silibinin (mixture of Silybin A and Silybin B)	Structural Classification Flavanonols Flavonoids Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Others
(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-135252

N-Desbutyroyl acebutolol Deacyl acebutolol; M and B 17127	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Desbutyroyl Acebutolol (compound Ⅲ) is a metabolite of Acebutolol (HY-17497) .

HY-109051C

Arfolitixorin sulfate	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Arfolitixorin sulfate is a potent 5-Fluorouracil (5-FU) moderator. Arfolitixorin sulfate is an immediately active form of Folate, [6R]-5,10-methylenetetrahydrofolate ([6R]-MTHF). Arfolitixorin sulfate is potent for the research of metastatic colorectal cancer .

HY-129566

Withanolide B	Classification of Application Fields Neurological Disease Source classification Metabolic Disease Withania somnifera Plants Solanaceae Disease Research Fields Inflammation/Immunology Steroids	ERK Wnt β-catenin
Withanolide B is an active component of W. somnifera Dunal. Withanolide B promotes osteogenic differentiation of hBMSCs via ERK1/2 and Wnt/β-catenin signaling pathways. Withanolide B exhibits neuroprotective, anti-arthritic, anti-aging and anti-cancer effects .

HY-111038

Capsiconiate Coniferyl (E)-8-methyl-6-nonenoate	Structural Classification Monophenols Source classification Phenols Plants Solanaceae Capsicum baccatum L.	TRP Channel
Capsiconiate (Coniferyl (E)-8-methyl-6-nonenoate) is a TRPV1 agonist (EC₅₀= 3.2 μM). Capsiconiate can be used to study TRPV1-mediated diseases such as pain, inflammation, and epilepsy(EC₅₀= 3.2 μM) .

HY-N1189

DL-Syringaresinol diacetate Syringaresinol Diacetate	Structural Classification Natural Products Source classification Plants Menispermaceae	Others
DL-Syringaresinol diacetate is a glucoside. DL-Syringaresinol inhibits cAMP phosphodiesterase and alleviation of stress .

HY-N9248

6-Hydroxywogonin

Structural Classification Flavonoids Microorganisms Flavones Source classification

Others

6-Hydroxywogonin (compound 26) is a flavonoid compound .

HY-N6927

Isoforskolin Coleonol B	Classification of Application Fields Terpenoids Labiatae Source classification Diterpenoids Plants Inflammation/Immunology Disease Research Fields Gochnatia polymorpha (Less) Cabr.	TNF Receptor Interleukin Related
Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis .

HY-N7575

Lacto-N-fucopentaose II LNFP II	Structural Classification Polysaccharides Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Cancer	Endogenous Metabolite
Lacto-N-fucopentaose II (LNFP II) is a sialyl-Lewis, hapten of human Lewis bloodgroup determinant. Lacto-N-fucopentaose II monosialo-ganglioside/glycolipid and sialyl derivative, CA 19-9, is a molecular tumour markers (TM) for biliopancreatic malignancy .

HY-121711

5-OH-HxMF	Structural Classification Flavonoids Flavones Source classification Rutaceae Plants Citrus reticulata Blanco	Apoptosis
5-OH-HxMF is a hydroxylated polymethoxyflavone that has anti-inflammatory, anticancer, neurotrophic and neuroprotective activities .

HY-N12141

Flaccidoside II	Structural Classification Polysaccharides Anemone flaccida Fr. Schmidt Source classification Ranunculaceae Plants Saccharides	Apoptosis
Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome .

HY-114519

Helenalin acetate 1 Publications Verification	Sesquiterpenes Source classification Derris robusta Plants Compositae	Histone Demethylase NF-κB
Helenalin acetate, a natural NF-κB inhibitor, is a potent C/EBPβ inhibitor. Helenalin acetate has anti-inflammatory and anticancer activities .

HY-N11576

Secalonic acid D	Structural Classification Natural Products Microorganisms Classification of Application Fields Sunscreen Source classification Cosmetic Research Disease Research Fields Cancer	Apoptosis GSK-3 c-Myc β-catenin
Secalonic acid D is a toxic compound against tumor cells. Secalonic acid D can be isolated from the metabolites of Aspergillus aculeatus. Secalonic acid D activates GSK3-β, and degrades β-catenin. Thus, Secalonic acid D down-regulates c-Myc expression, arrests cell cycle at G1 phase, induces cell apoptosis .

HY-P1680

Astin C Asterin	Structural Classification Natural Products Source classification Plants Compositae Erythrina latissima E. Mey.	Others
Astin C (Asterin) is a cyclic pentapeptide with anticancer and anti-inflammatory properties .

HY-N12307

Gentiiridosides A	Structural Classification Monophenols Ketones, Aldehydes, Acids Source classification Gentianaceae Phenols Gentianella acuta (Michx.) Hulten Plants Saccharides Monosaccharides	Others
Gentiiridosides A is EtOH extract from Gentianella acuta .

HY-N3883

Euxanthone	Structural Classification Flavonoids Garcinia oblongifolia Champ. ex Benth. Source classification Guttiferae Plants Other Flavonoids	Autophagy
Euxanthone, a xanthone derivative, attenuates Aβ1-42-induced oxidative stress and apoptosis by triggering autophagy. Euxanthone exhibits anti-neoplastic and neuroprotective activities .

HY-Y0921

(±)-1,2-Propanediol 1 Publications Verification 1,2-(RS)-Propanediol; 1,2-Propylene glycol; Propylene glycol	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease markers Other Diseases Endogenous metabolite Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
(±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

HY-N3497

Isochamaejasmin	Structural Classification Flavonoids Thymelaeaceae Stellera chamaejasme Linn. Plants Other Flavonoids	NF-κB DNA/RNA Synthesis Parasite Apoptosis
Isochamaejasmin is a biflavonoid with anti-cancer, antiplasmodial and insecticidal activities. Isochamaejasmin displays a potent NF-κB (NF-κB) activation activity. Isochamaejasmin could cause DNA damage and induce apoptosis via the mitochondrial pathway in AW1 cells . Isochamaejasmin also has a moderate antiplasmodial activity (IC₅₀ of 7.3 μM for *P. falciparum*) and relatively low cytotoxicity (CC₅₀ of 29.0 μM) .

HY-N6033

Ferruginol (+)-Ferruginol	Structural Classification Cupressaceae Terpenoids Diterpenoids Thuja standishii (Gord.) Carr. Plants	EBV HSV Apoptosis
Ferruginol ((+)-Ferruginol), a natural diterpenoid, is an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). Ferruginol inhibits the growth of thyroid cancer cells through the induction of mitochondrial apoptosis. Ferruginol has antitumor, cardioprotective, antioxidant, gastroprotective, and neuroprotective activities .

HY-N2894

Piperolactam A	Structural Classification Alkaloids Piper betle L. Source classification Piperaceae Plants	Parasite
Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani .

HY-136699

Excisanin A	Structural Classification Terpenoids Labiatae Source classification Diterpenoids Plants Baccharis densiflora Wedd.	Others
Excisanin A is a potent anticancer agent. Excisanin A inhibits cell proliferation, migration, adhesion and invasion. Excisanin A decreases the expression of MMP-2, MMP-9, p-FAK, p-Src, integrin β1 protein. Excisanin A has the potential for the research of breast cancer .

HY-N8915

Deoxyflindissone	Triterpenes Structural Classification Cornaceae Terpenoids Source classification Cornus walteri Wangerin Plants	Others
Deoxyflindissone (Compound 13) is a triterpenoid compound. Deoxyflindissone is isolated from natural Cornus walteri .Deoxyflindissone has significant cytotoxic activity .

HY-125570

Ginsenoside Rs3	Structural Classification Polysaccharides Source classification Plants Talinaceae Saccharides Talinum paniculatum (Jacq.) Gaertn.	Apoptosis
Ginsenoside Rs3 is a natural diol-type ginseng saponin with anticancer effects. Ginsenoside Rs3 selectively elevates protein levels of p53 and p21WAF1 leading to induction of apoptosis in SK-HEP-1 cells .

HY-N12128

Ophiopogonin R	Ophiopogon japonicus (L. f.) Ker-Gawl. Structural Classification Polysaccharides Liliaceae Source classification Plants Saccharides	Others
Ophiopogonin R (compound 3) is a steroid saponin. Ophiopogonin R was isolated and purified from natural ophiopogonin. Ophiopogonin R was not cytotoxic to five human tumor cell lines (HepG2, HLE, BEL7402, BEL7403 and Hela) .

HY-N12200

Mollicellin I	Structural Classification Natural Products Microorganisms Source classification	Others
Mollicellin I (compound 1) is a depsidone. The growth inhibitory activity of Mollicellin I on human breast cancer (Bre04), human lung (Lu04) and human neuroma (N04) cell lines is not significant, with GI₅₀s >10 μg/mL .

HY-N12041

Axl-IN-16	Structural Classification Natural Products Microorganisms Source classification	TAM Receptor HIF/HIF Prolyl-Hydroxylase
Axl-IN-16 is a dual inhibitor of Axl/HIF. Axl-IN-16 induces fruiting body formation of Flammulina velutipes. Axl-IN-16 inhibits hypoxia-inducible factor activity and receptor tyrosine kinase expression .

HY-N8764

Decaffeoylacteoside Decaffeoylverbascoside; Verbasoside	Structural Classification Labiatae Source classification Phenols Polyphenols Plants Ambrosia hispida	Monoamine Oxidase Cholinesterase (ChE)
Decaffeoylacteoside is an inhibitor of AChE/BChE/LOX with moderate activity .

HY-B1472

Deoxycorticosterone acetate 11-Deoxycorticosterone acetate; DOC acetate; Cortexone acetate	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Mineralocorticoid Receptor Endogenous Metabolite
Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria .

HY-W007511

4-Methyl-1-pentanol Isohexanol	Structural Classification Natural Products Microorganisms Classification of Application Fields Nicotiana tabacum L. Source classification Other Diseases Plants Solanaceae Disease Research Fields	Others
4-Methyl-1-pentanol (Isohexanol) is a pentanol added with methyl group, which can be used as a solvent and has excellent synergistic effect with PVCap. 4-Methyl-1-pentanol is also a volatile aroma component of red wine, which is often used in the production and blending of wine. 4-Methyl-1-pentanol can also be used as an alcohol antagonist to antagonize the effects of ethanol and 1-butanol on L1-mediated cell-cell adhesion, and is used in the study of fetal alcohol syndrome .

HY-N3831

Epimedokoreanin B	Structural Classification Flavonoids Flavones Epimedium koreanum Nakai Source classification Plants Berberidaceae	Bacterial Apoptosis
Epimedokoreanin B is a natural flavonoid with anticancer, anti-inflammatory and antibacterial effects. Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated apoptosis accompanied by autophagosome accumulation. Epimedokoreanin B is an anti-periodontitis agent that inhibits gingipains and *Porphyromonas gingivalis* growth and biofilm formation .

HY-N10378

Rubrofusarin 6-O-β-D-glucopyranoside	Monophenols Classification of Application Fields Neurological Disease Cassia obtusifolia L. Source classification Phenols Metabolic Disease Caesalpiniaceae Plants Disease Research Fields	Phosphatase
Rubrofusarin 6-O-β-D-glucopyranoside, the glycoside of Rubrofusarin, is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with the IC₅₀ of 87.36 μM. Rubrofusarin 6-O-β-D-glucopyranoside can be used for the research of comorbid diabetes and depression .

HY-108307

Micronomicin sulfate Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate	Infection Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .

HY-N0452

Hyperoside 4 Publications Verification	Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Guttiferae Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Hypericum monogynum L.	Influenza Virus Fungal NF-κB Apoptosis
Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-147089

PRRSV/CD163-IN-1	Infection Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Bacterial Endogenous Metabolite
PRRSV/CD163-IN-1 is a PRRSV/CD163 inhibitor. PRRSV/CD163-IN-1 can inhibit the interaction between the PRRSV glycoprotein (GP2a or GP4) and the CD163-SRCR5 domain. PRRSV/CD163-IN-1 can be used for the research of porcine reproductive and respiratory syndrome (PRRS) .

HY-N8646

Isodonal	Structural Classification Terpenoids Labiatae Source classification Cirsium palustre (L.) Scop. Diterpenoids Plants	Others
Isodonal is a N-pentane diterpene compound with potential cytotoxic, antitumor, inhibitory oxidative phosphorylation and antiingestion activities. Isodonal can be isolated from the leaves of Isodon wikstroemioides and is used in the study of gastrointestinal diseases, anti-tumor and anti-inflammatory .

HY-N12198

Mollicellin H	Structural Classification Natural Products Microorganisms Source classification	Others
Mollicellin H is a secondary metabolite of the fungus C. brasiliense and has a wide range of biological activities, including immunomodulation, cytotoxicity and anti-tumor effects. The growth inhibitory effects (GI₅₀s) of Mollicellin H on human breast cancer (Bre04), human lung (Lu04) and human neuroma (N04) cell lines are 5.1 μg/mL, 6.5 μg/mL and 2.5 μg/mL respectively .

HY-W145516

Guar gum	Structural Classification Natural Products Leguminosae Source classification Cyamopsis tetragonoloba (L.) Taub. Plants	Biochemical Assay Reagents
Guar gum is a versatile polymer for drug delivery applications. Guar gum diaplays thickening, emulsifying, binding and gelling properties, quick solubility in cold water, wide pH stability, film forming ability and biodegradability, it finds applications in large number of industries. Guar gum can be isolated from the powdered endosperm of the seeds of the Cyamopsis tetragonolobus. Guar gum can be used as an excipient, such as thickener, suspending agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-B2221

Cellulose Pectin glycosidase	Structural Classification Polysaccharides Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields Saccharides	Endogenous Metabolite
Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food.

HY-N11684

Cocoa butter	Structural Classification Natural Products Source classification Sterculiaceae Theobroma cacao Linn. Plants	Biochemical Assay Reagents
Cocoa butter can be used as an excipient, such as lubricants, suppository bases. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-W250795

Maltodextrin, dextrose equivalent 16.5-19.5 Maltodextrin; Dextrin maize starch	Structural Classification Polysaccharides Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
Maltodextrin, dextrose equivalent 16.5-19.5 can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-P2853

Hemocyanin	Structural Classification Natural Products Animals Source classification	Endogenous Metabolite
Hemocyanin is a large copper-containing respiratory protein. Hemocyanin is an important non-specific innate immune defense molecule with phenoloxidase, antiviral, antibacterial, hemolytic, and antitumor activities .

Cat. No.	Product Name	Chemical Structure

HY-Z5058S

(3R,5S)-Fluvastatin-d7 sodium

(3R,5S)-Fluvastatin-d₇ (sodium) is the deuterium labeled (3R,5S)-Fluvastatin sodium[1].

HY-W040240S

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one-13C
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- ¹³C is the ¹³C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].

HY-146708S

((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate-15N4 sodium
((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- ¹⁵N₄ (sodium) is a ¹⁵N-labeled ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate (so

HY-W040240S1

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one-13C-1
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- ¹³C-1 is the ¹³C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].

HY-W040240S2

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one-13C-2
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- ¹³C-2 is the ¹³C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].

HY-W011090S

((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate-13C9,15N3 sodium
((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- ¹³C₉, ¹⁵N₃ (sodium) is the ¹³C and ¹⁵N labeled Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate[1].

HY-N1459S

(24Rac)-Campesterol-d7
Campesterol-d₇ ((24R)-5-Ergosten-3β-ol-d₇) is the deuterium labeled Campesterol. Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

HY-132485S

N-Methyl Pantoprazole-d3 (Mixture of 1 and 3 isomers)

N-Methyl Pantoprazole-d3 (Mixture of 1 and 3 isomers) is the deuterium labeled N-Methyl Pantoprazole (Mixture of 1 and 3 isomers) .
HY-146909S

CER5-2’R-d9

CER5-2’R-d₉ is deuterium labeled CER5-2’R.
HY-108226S

Regorafenib N-oxide and N-desmethyl (M5)-d3

Regorafenib N-oxide and N-desmethyl (M5)-d₃ is deuterium labeled Regorafenib N-oxide and N-desmethyl (M5).
HY-108226S1

Regorafenib N-oxide and N-desmethyl (M5)-13C6

Regorafenib N-oxide and N-desmethyl (M5)- ¹³C₆ is the ¹³C-labeled Regorafenib N-oxide and N-desmethyl (M5)[1].

HY-B2221S1

U-13C Cellulose from chicory

U- ¹³C Cellulose from chicory is the ¹³C labeled Cellulose (HY-B2221). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .

HY-B2221S

U-13C Cellulose high DP from potato

U- ¹³C Cellulose high DP from potato is the ¹³C labeled Cellulose (HY-B2221). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .

HY-B2221S3

U-13C Cellulose high DP from maize

U- ¹³C Cellulose high DP from maize is the ¹³C labeled Cellulose (HY-B2221). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .

HY-129812

Borofalan

Borofalan- ¹⁰B can be used for Boron neutron capture research (BNCT). Borofalan- ¹⁰B can be used for the research of recurrent or locally advanced head and neck cancer .

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